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Tesofensine

Also known as: NS2330

A triple monoamine reuptake inhibitor that reduces appetite and increases thermogenesis through central nervous system pathways.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~220 hours

Typical Dose

0.5 mg daily

Administration

Oral

Mechanism of Action

Blocks reuptake of serotonin, dopamine, and norepinephrine simultaneously, creating profound appetite suppression and metabolic acceleration.

Key Research Areas

weight lossappetiteoralCNSthermogenesis

Frequently Asked Questions

What is Tesofensine?
A triple monoamine reuptake inhibitor that reduces appetite and increases thermogenesis through central nervous system pathways.
How does Tesofensine work?
Blocks reuptake of serotonin, dopamine, and norepinephrine simultaneously, creating profound appetite suppression and metabolic acceleration.
What is the recommended dosage for Tesofensine?
The typical research dosage is 0.5 mg daily, administered via Oral. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of Tesofensine?
The half-life of Tesofensine is approximately ~220 hours. This affects dosing frequency and timing in research protocols.
Is Tesofensine FDA approved?
Tesofensine is currently classified as "Clinical Trials" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.

Research Disclaimer

The information provided about Tesofensine is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

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