MitochondrialResearch
AICAR
Also known as: Acadesine
An AMPK activator studied for endurance enhancement and metabolic effects. Sometimes called an exercise-in-a-pill compound.
Reviewed by Dr. Sarah Mitchell, PharmD, BCPS
Lead Researcher · 12+ years in peptide therapeutics
Half-Life
~2–3 hours
Typical Dose
Research dosing
Administration
Subcutaneous injection
Mechanism of Action
Directly activates AMP-activated protein kinase, shifting metabolism toward fat oxidation and mimicking the metabolic effects of exercise.
Key Research Areas
AMPKenduranceexercise mimeticmetabolism
Frequently Asked Questions
What is AICAR?▾
An AMPK activator studied for endurance enhancement and metabolic effects. Sometimes called an exercise-in-a-pill compound.
How does AICAR work?▾
Directly activates AMP-activated protein kinase, shifting metabolism toward fat oxidation and mimicking the metabolic effects of exercise.
What is the recommended dosage for AICAR?▾
The typical research dosage is Research dosing, administered via Subcutaneous injection. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of AICAR?▾
The half-life of AICAR is approximately ~2–3 hours. This affects dosing frequency and timing in research protocols.
Is AICAR FDA approved?▾
AICAR is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.
Research Disclaimer
The information provided about AICAR is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.