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Anti-AgingResearch

NAD+

Also known as: Nicotinamide Adenine Dinucleotide · NAD

A coenzyme present in every living cell, critical for energy metabolism and cellular repair. NAD+ levels decline with age; replenishment is a cornerstone of modern longevity medicine.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~45 minutes (IV)

Typical Dose

250–500 mg (IV) or 100–300 mg (subcutaneous)

Administration

IV infusion or subcutaneous injection

Mechanism of Action

Fuels mitochondrial ATP production, activates sirtuin longevity pathways, and supports PARP DNA-repair enzymes.

Key Research Areas

anti-agingenergylongevitymitochondriasirtuins

Frequently Asked Questions

What is NAD+?
A coenzyme present in every living cell, critical for energy metabolism and cellular repair. NAD+ levels decline with age; replenishment is a cornerstone of modern longevity medicine.
How does NAD+ work?
Fuels mitochondrial ATP production, activates sirtuin longevity pathways, and supports PARP DNA-repair enzymes.
What is the recommended dosage for NAD+?
The typical research dosage is 250–500 mg (IV) or 100–300 mg (subcutaneous), administered via IV infusion or subcutaneous injection. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of NAD+?
The half-life of NAD+ is approximately ~45 minutes (IV). This affects dosing frequency and timing in research protocols.
Is NAD+ FDA approved?
NAD+ is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.

Research Disclaimer

The information provided about NAD+ is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

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