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ClinicalFDA Approved

Leuprorelin

Also known as: Leuprolide · Lupron · Eligard

A potent GnRH agonist used for prostate cancer, endometriosis, precocious puberty, and gender-affirming hormone suppression.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~3 hours

Typical Dose

3.75–22.5 mg depot monthly/quarterly

Administration

IM or SC depot injection

Mechanism of Action

Continuous GnRH receptor stimulation causes initial flare then complete pituitary desensitization, achieving reversible chemical castration.

Key Research Areas

clinicalFDA approvedprostate cancerendometriosis

Frequently Asked Questions

What is Leuprorelin?
A potent GnRH agonist used for prostate cancer, endometriosis, precocious puberty, and gender-affirming hormone suppression.
How does Leuprorelin work?
Continuous GnRH receptor stimulation causes initial flare then complete pituitary desensitization, achieving reversible chemical castration.
What is the recommended dosage for Leuprorelin?
The typical research dosage is 3.75–22.5 mg depot monthly/quarterly, administered via IM or SC depot injection. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of Leuprorelin?
The half-life of Leuprorelin is approximately ~3 hours. This affects dosing frequency and timing in research protocols.
Is Leuprorelin FDA approved?
Yes, Leuprorelin is FDA approved for specific medical indications. Consult your physician for proper medical guidance.

Research Disclaimer

The information provided about Leuprorelin is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

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