PeptidePicker
Get Started
Home/Peptides/Kisspeptin
Sexual HealthResearch

Kisspeptin

Also known as: KISS-1 · Metastin · KP-10

The upstream master switch of the reproductive HPG axis. The cleanest method to restore endogenous testosterone and support fertility without HPTA suppression.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~28 minutes

Typical Dose

100–200 mcg

Administration

Subcutaneous injection

Mechanism of Action

Activates Kiss1R receptors on GnRH neurons, triggering pulsatile gonadotropin release to naturally restore testosterone and gonadal function.

Key Research Areas

fertilitytestosteronehormoneHPG axisreproductive

Frequently Asked Questions

What is Kisspeptin?▾
The upstream master switch of the reproductive HPG axis. The cleanest method to restore endogenous testosterone and support fertility without HPTA suppression.
How does Kisspeptin work?▾
Activates Kiss1R receptors on GnRH neurons, triggering pulsatile gonadotropin release to naturally restore testosterone and gonadal function.
What is the recommended dosage for Kisspeptin?▾
The typical research dosage is 100–200 mcg, administered via Subcutaneous injection. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of Kisspeptin?▾
The half-life of Kisspeptin is approximately ~28 minutes. This affects dosing frequency and timing in research protocols.
Is Kisspeptin FDA approved?▾
Kisspeptin is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.

Research Disclaimer

The information provided about Kisspeptin is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

Related Peptides in Sexual Health

PT-141

Bremelanotide · Vyleesi

Back to All PeptidesFind Your Peptide — Take the Quiz