AntimicrobialResearch
Alpha-Defensin 1
Also known as: HNP-1 · DEFA1
An endogenous antimicrobial peptide from human neutrophils that shreds bacterial membranes and bridges innate-to-adaptive immune memory.
Reviewed by Dr. Sarah Mitchell, PharmD, BCPS
Lead Researcher · 12+ years in peptide therapeutics
Half-Life
~2–4 hours
Typical Dose
Research dosing
Administration
Research
Mechanism of Action
Forms pores in microbial membranes through voltage-dependent channels while simultaneously activating dendritic cells for adaptive immunity.
Key Research Areas
antimicrobialimmuneneutrophilinnate defense
Frequently Asked Questions
What is Alpha-Defensin 1?▾
An endogenous antimicrobial peptide from human neutrophils that shreds bacterial membranes and bridges innate-to-adaptive immune memory.
How does Alpha-Defensin 1 work?▾
Forms pores in microbial membranes through voltage-dependent channels while simultaneously activating dendritic cells for adaptive immunity.
What is the recommended dosage for Alpha-Defensin 1?▾
The typical research dosage is Research dosing, administered via Research. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of Alpha-Defensin 1?▾
The half-life of Alpha-Defensin 1 is approximately ~2–4 hours. This affects dosing frequency and timing in research protocols.
Is Alpha-Defensin 1 FDA approved?▾
Alpha-Defensin 1 is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.
Research Disclaimer
The information provided about Alpha-Defensin 1 is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.